CMap Candidate Details

Structure:
CMap ID: C12458
Pert ID: BRD-K31699485
Compound Name: DMeOB
Targets: GRM5
MoA: Glutamate receptor modulator
SMILES: COc1cccc(C=NC=Nc2cccc(OC)c2)c1
InchiKey: CWHVUMNEZIBZFC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2861 BRD-K31699485 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3351 BRD-K31699485 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3611 BRD-K31699485 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3949 BRD-K31699485 VCAP 10 uM 6 h 0.0 0.0 0.0 0.32 1.13 0.84
44359 BRD-K31699485 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44692 BRD-K31699485 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45219 BRD-K31699485 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45488 BRD-K31699485 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45801 BRD-K31699485 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46037 BRD-K31699485 NPC 10 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
46353 BRD-K31699485 PHH 10 uM 24 h -0.18 -0.74 0.0 -0.29 -0.96 0.43
46671 BRD-K31699485 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).