CMap Candidate Details

Structure:
CMap ID: C01246
Pert ID: BRD-A52172093
Compound Name: VU-0413807-2
Targets: CACNA1I; CACNA1H; CACNA1G
MoA: Calcium channel blocker
SMILES: CC(C)(C)CCN1C[C@H]2C(CNC(=O)c3cc(Cl)cc(Cl)c3)[C@H]2C1
InchiKey: GSJIGYLGKSBYBC-ALOPSCKCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16494 BRD-A52172093 A375 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.36 2.02
16542 BRD-A52172093 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
16869 BRD-A52172093 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17195 BRD-A52172093 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17534 BRD-A52172093 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17876 BRD-A52172093 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
18380 BRD-A52172093 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
18668 BRD-A52172093 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).