CMap Candidate Details

Structure:
CMap ID: C01249
Pert ID: BRD-A52282606
Compound Name: lacidipine
Targets: CACNA1C
MoA: Calcium channel blocker
SMILES: CCOC(=O)C1C(C(=C(C)N=C1C)C(=O)OCC)c2ccccc2/C=C/C(=O)OC(C)(C)C
InchiKey: BGYJFSXPRMOZJK-CCEZHUSRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24389 BRD-A52282606 A375 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
24535 BRD-A52282606 A549 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
24728 BRD-A52282606 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24848 BRD-A52282606 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25071 BRD-A52282606 MCF??7.00 10 uM 6 h -0.22 -0.93 0.07 0.31 1.09 0.68
25131 BRD-A52282606 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25299 BRD-A52282606 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).