CMap Candidate Details

Structure:
CMap ID: C12516
Pert ID: BRD-K31843556
Compound Name: T-0070907
Targets: PPARG
MoA: PPAR receptor antagonist
SMILES: [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc1ccncc1
InchiKey: FRPJSHKMZHWJBE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3006 BRD-K31843556 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3172 BRD-K31843556 HCC515 10 uM 24 h 0.27 1.14 0.31 0.28 0.98 0.38
3481 BRD-K31843556 PC3 10 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
3766 BRD-K31843556 VCAP 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
44361 BRD-K31843556 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44694 BRD-K31843556 A549 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.32
44919 BRD-K31843556 ASC 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
45221 BRD-K31843556 HEPG2 10 uM 6 h 0.28 1.18 0.39 0.31 1.1 0.68
45490 BRD-K31843556 HT29 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.79 0.1
45680 BRD-K31843556 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.3 1.08 0.65
46355 BRD-K31843556 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46673 BRD-K31843556 SKB 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.76 0.07
99836 BRD-K31843556 U2OS 10 uM 6 h -0.2 -0.83 0.0 -0.38 -1.28 1.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).