CMap Candidate Details

Structure:
CMap ID: C12546
Pert ID: BRD-K31912990
Compound Name: CGP-71683
Targets: NPY5R
MoA: Neuropeptide receptor antagonist
SMILES: Nc1nc(NCC2CCC(CNS(=O)(=O)c3cccc4ccccc34)CC2)nc5ccccc15
InchiKey: UULIGRNKXHCLQN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4095 BRD-K31912990 HA1E 10 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.15
4413 BRD-K31912990 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4676 BRD-K31912990 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4920 BRD-K31912990 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.25
37141 BRD-K31912990 A375 10 uM 6 h -0.25 -1.03 0.2 0.0 0.0 0.0
37279 BRD-K31912990 A549 10 uM 24 h -0.2 -0.82 0.0 0.22 0.77 0.06
37633 BRD-K31912990 ASC 10 uM 24 h -0.3 -1.23 0.64 0.41 1.46 2.23
37893 BRD-K31912990 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.45 15.35
38072 BRD-K31912990 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38195 BRD-K31912990 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.48 -1.61 15.65
38460 BRD-K31912990 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99837 BRD-K31912990 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).