CMap Candidate Details
Structure:
| CMap ID: | C01258 |
| Pert ID: | BRD-A52627843 |
| Compound Name: | thiostrepton |
| Targets: | FOXM1 |
| MoA: | FOXM1 inhibitor; Protein synthesis inhibitor |
| SMILES: | CCC(C)[C@@H]1N[C@@H]2C=Cc3c(cc(nc3[C@H]2O)C(=O)O[C@H](C)[C@@H]2NC(=O)c3csc(n3)[C@@H](NC(=O)[C@H]3CSC(=N3)C(NC(=O)[C@@H](NC(=O)c3csc(n3)[C@]3(CCC(=N[C@H]3c3csc2n3)c2nc(cs2)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)NC(=O)[C@H](C)NC(=O)C(=C)NC(=O)[C@H](C)NC1=O)[C@@H](C)O)=CC)[C@@](C)(O)[C@@H](C)O)[C@H](C)O |
| InchiKey: | NSFFHOGKXHRQEW-MWCLUCFNSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 51677 | BRD-A52627843 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.46 | -1.55 | 15.35 |
| 51785 | BRD-A52627843 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |