CMap Candidate Details

Structure:
CMap ID: C00126
Pert ID: BRD-A04706586
Compound Name: bucladesine
Targets: PRKACA
MoA: CAMP stimulant; Adenosine receptor agonist
SMILES: CCCC(=O)Nc1ncnc2n(cnc12)C3OC4COP(=O)(O)OC4C3OC(=O)CCC
InchiKey: CJGYSWNGNKCJSB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7048 BRD-A04706586 A549 10 uM 6 h -0.27 -1.13 0.41 -0.36 -1.2 1.22
8856 BRD-A04706586 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9263 BRD-A04706586 AGS 10 uM 6 h 0.17 0.72 0.0 0.0 0.0 0.0
9565 BRD-A04706586 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9951 BRD-A04706586 HA1E 10 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.66
10323 BRD-A04706586 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10379 BRD-A04706586 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11096 BRD-A04706586 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11206 BRD-A04706586 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11635 BRD-A04706586 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.63
12526 BRD-A04706586 PC3 10 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
12642 BRD-A04706586 SW480 10 uM 6 h -0.2 -0.82 0.0 0.0 0.0 0.0
13052 BRD-A04706586 THP1 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
13124 BRD-A04706586 U937 10 uM 6 h -0.29 -1.2 0.55 0.0 0.0 0.0
13413 BRD-A04706586 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53418 BRD-A04706586 HEPG2 2.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53542 BRD-A04706586 HUH7 10 uM 6 h -0.19 -0.78 0.0 0.0 0.0 0.0
53625 BRD-A04706586 PHH 2.5 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).