CMap Candidate Details

Structure:
CMap ID: C01260
Pert ID: BRD-A52650764
Compound Name: ingenol
Targets: PRKCD; PRKCE
MoA: PKC activator
SMILES: CC1CC2C(C3C=C(COC(=O)c4ccccc4)C(O)C4(O)C(OC(=O)c5ccccc5)C(C)=CC14C3=O)C2(C)C
InchiKey: GIMKEHNOTHXONN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8878 BRD-A52650764 A375 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
9294 BRD-A52650764 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9596 BRD-A52650764 H1299 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
9929 BRD-A52650764 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10179 BRD-A52650764 HCC515 10 uM 24 h -0.25 -1.02 0.18 -0.52 -1.77 15.65
10404 BRD-A52650764 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10671 BRD-A52650764 HEPG2 10 uM 6 h -0.21 -0.86 0.02 -0.45 -1.52 15.35
11086 BRD-A52650764 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11345 BRD-A52650764 NCIH2073 10 uM 6 h -0.25 -1.04 0.22 -0.45 -1.52 15.35
11657 BRD-A52650764 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11918 BRD-A52650764 NCIH596 10 uM 6 h -0.23 -0.95 0.09 -0.56 -1.87 15.65
12500 BRD-A52650764 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12670 BRD-A52650764 SW480 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.45
13152 BRD-A52650764 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13538 BRD-A52650764 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.44 -1.47 15.35
90526 BRD-A52650764 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97648 BRD-A52650764 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
97686 BRD-A52650764 NKDBA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).