CMap Candidate Details

Structure:
CMap ID: C01261
Pert ID: BRD-A52660433
Compound Name: tetrindole
Targets: MAOA
MoA: Monoamine oxidase inhibitor
SMILES: C1CCC(CC1)c1ccc2n3CCNC4CCCc(c34)c2c1
InchiKey: AUXCHYJDVJZEPG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6842 BRD-A52660433 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7085 BRD-A52660433 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7237 BRD-A52660433 HA1E 10 uM 24 h 0.2 0.85 0.0 0.33 1.15 0.89
7555 BRD-A52660433 HCC515 10 uM 6 h 0.0 0.0 0.0 0.35 1.24 1.24
7955 BRD-A52660433 HT29 10 uM 6 h -0.28 -1.15 0.44 0.0 0.0 0.0
8308 BRD-A52660433 PC3 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
8588 BRD-A52660433 VCAP 10 uM 24 h -0.29 -1.22 0.61 0.26 0.91 0.23
100209 BRD-A52660433 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124345 BRD-A52660433 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124408 BRD-A52660433 JURKAT 1.11 uM 24 h 0.21 0.87 0.01 -0.38 -1.26 1.38
124447 BRD-A52660433 MCF10A 0.37 uM 24 h -0.28 -1.16 0.46 0.0 0.0 0.0
124462 BRD-A52660433 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124539 BRD-A52660433 YAPC 10 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.29
132416 BRD-A52660433 HEK293 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
132546 BRD-A52660433 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132596 BRD-A52660433 THP1 0.74 uM 24 h -0.22 -0.92 0.06 -0.23 -0.77 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).