CMap Candidate Details

Structure:
CMap ID: C12614
Pert ID: BRD-K32101625
Compound Name: LX-1031
Targets: --
MoA: --
SMILES: COc1cccc(c1)-c1ccc(cc1)[C@@H](Oc1cc(nc(N)n1)-c1ccc(C[C@H](N)C(O)=O)cc1)C(F)(F)F
InchiKey: XNMUICFMGGQSMZ-WIOPSUGQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120516 BRD-K32101625 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120551 BRD-K32101625 A549 0.04 uM 24 h 0.0 0.0 0.0 0.41 1.45 2.22
120652 BRD-K32101625 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120702 BRD-K32101625 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120774 BRD-K32101625 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120808 BRD-K32101625 YAPC 0.04 uM 24 h -0.21 -0.86 0.01 0.0 0.0 0.0
129003 BRD-K32101625 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129032 BRD-K32101625 HELA 0.01 uM 3 h 0.0 0.0 0.0 -0.23 -0.78 0.09
129051 BRD-K32101625 MCF??7.00 0.03 uM 24 h -0.21 -0.86 0.01 -0.24 -0.8 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).