CMap Candidate Details

Structure:
CMap ID: C12664
Pert ID: BRD-K32247306
Compound Name: primidone
Targets: GABRA1; GABRA2; GABRA3; GABRA4; GABRA5; GABRA6; GABRB1; GABRB2; GABRB3; GABRD; GABRE; GABRG1; GABRG2; GABRG3; GABRP; GABRQ
MoA: GABA receptor antagonist
SMILES: CCC1(C(=O)NCNC1=O)c1ccccc1
InchiKey: DQMZLTXERSFNPB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5315 BRD-K32247306 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5610 BRD-K32247306 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5900 BRD-K32247306 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37634 BRD-K32247306 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38073 BRD-K32247306 HT29 10 uM 6 h -0.2 -0.85 0.01 -0.21 -0.72 0.04
38940 BRD-K32247306 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51141 BRD-K32247306 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120517 BRD-K32247306 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120552 BRD-K32247306 A549 1.11 uM 24 h -0.3 -1.24 0.64 0.26 0.91 0.24
120703 BRD-K32247306 JURKAT 10 uM 24 h -0.23 -0.95 0.09 -0.33 -1.1 0.87
120809 BRD-K32247306 YAPC 3.33 uM 24 h -0.27 -1.12 0.39 -0.28 -0.95 0.4
129019 BRD-K32247306 HELA 0.03 uM 24 h 0.23 0.95 0.06 0.49 1.72 2.56
129052 BRD-K32247306 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
129077 BRD-K32247306 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).