CMap Candidate Details

Structure:
CMap ID: C00127
Pert ID: BRD-A04756508
Compound Name: norgestimate
Targets: PGR
MoA: Progesterone receptor agonist
SMILES: CC[C@]12CCC3C(CCC4=CC(CCC34)=NO)C1CC[C@@]2(OC(C)=O)C#C
InchiKey: KIQQMECNKUGGKA-OMEWWMGKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5247 BRD-A04756508 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5488 BRD-A04756508 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5815 BRD-A04756508 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5970 BRD-A04756508 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6230 BRD-A04756508 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6446 BRD-A04756508 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37037 BRD-A04756508 A375 10 uM 6 h -0.24 -0.98 0.12 0.0 0.0 0.0
37211 BRD-A04756508 A549 10 uM 24 h -0.3 -1.25 0.71 0.0 0.0 0.0
37431 BRD-A04756508 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38124 BRD-A04756508 MCF??7.00 10 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
38285 BRD-A04756508 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
38595 BRD-A04756508 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).