CMap Candidate Details

Structure:
CMap ID: C12745
Pert ID: BRD-K32501161
Compound Name: vanoxerine
Targets: SLC6A3
MoA: Dopamine uptake inhibitor
SMILES: Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1
InchiKey: NAUWTFJOPJWYOT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2864 BRD-K32501161 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3175 BRD-K32501161 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3484 BRD-K32501161 PC3 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
3767 BRD-K32501161 VCAP 10 uM 24 h -0.18 -0.74 0.0 -0.32 -1.09 0.81
44563 BRD-K32501161 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44925 BRD-K32501161 ASC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
45225 BRD-K32501161 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45682 BRD-K32501161 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
46360 BRD-K32501161 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98369 BRD-K32501161 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98687 BRD-K32501161 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99844 BRD-K32501161 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120520 BRD-K32501161 A375 10 uM 24 h 0.24 1.0 0.11 -0.3 -1.02 0.6
120618 BRD-K32501161 HELA 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.94
120655 BRD-K32501161 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120707 BRD-K32501161 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120814 BRD-K32501161 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.8
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).