CMap Candidate Details

Structure:
CMap ID: C12772
Pert ID: BRD-K32584078
Compound Name: BML-257
Targets: AKT1
MoA: Akt inhibitor; HCV inhibitor
SMILES: OC(=O)c1ccc2nc(c3ccccc3)c(nc2c1)c4ccccc4
InchiKey: LFWGZXMTCUOPFI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4097 BRD-K32584078 HA1E 10 uM 24 h 0.25 1.06 0.18 0.22 0.78 0.06
4414 BRD-K32584078 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4798 BRD-K32584078 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4922 BRD-K32584078 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39118 BRD-K32584078 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39441 BRD-K32584078 A549 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.32
39983 BRD-K32584078 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40258 BRD-K32584078 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.13 0.97
40611 BRD-K32584078 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.07
99846 BRD-K32584078 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).