CMap Candidate Details

Structure:
CMap ID: C12783
Pert ID: BRD-K32610195
Compound Name: androstenedione
Targets: HSD3B1; HSD17B1; AKR1C3
MoA: Cytochrome P450 inhibitor
SMILES: C[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CCC1=O
InchiKey: AEMFNILZOJDQLW-QAGGRKNESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33661 BRD-K32610195 A375 10 uM 6 h 0.24 1.0 0.11 0.0 0.0 0.0
34081 BRD-K32610195 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34596 BRD-K32610195 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34865 BRD-K32610195 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35127 BRD-K32610195 HT29 10 uM 6 h -0.22 -0.93 0.07 -0.29 -0.99 0.5
35443 BRD-K32610195 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35765 BRD-K32610195 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36073 BRD-K32610195 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36243 BRD-K32610195 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
36536 BRD-K32610195 SKB 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
36805 BRD-K32610195 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96132 BRD-K32610195 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99026 BRD-K32610195 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).