CMap Candidate Details

Structure:
CMap ID: C12810
Pert ID: BRD-K32710582
Compound Name: EI-247
Targets: INSR
MoA: IGF-1 inhibitor
SMILES: O[C@H](c1ccc2ccccc2c1)P(O)(O)=O
InchiKey: AMJJLDJPDLKNJA-NSHDSACASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33695 BRD-K32710582 A375 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.52
33797 BRD-K32710582 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34083 BRD-K32710582 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
34346 BRD-K32710582 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34598 BRD-K32710582 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35128 BRD-K32710582 HT29 10 uM 6 h 0.0 0.0 0.0 -0.18 -0.62 0.0
35467 BRD-K32710582 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35767 BRD-K32710582 NPC 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
35951 BRD-K32710582 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36245 BRD-K32710582 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36538 BRD-K32710582 SKB 10 uM 24 h -0.28 -1.18 0.51 0.0 0.0 0.0
36807 BRD-K32710582 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).