CMap Candidate Details

Structure:
CMap ID: C12841
Pert ID: BRD-K32821942
Compound Name: azathioprine
Targets: PPAT
MoA: Dehydrogenase inhibitor
SMILES: Cn1cnc(c1Sc1[nH]cnc2ncnc12)[N+]([O-])=O
InchiKey: LMEKQMALGUDUQG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1207 BRD-K32821942 PC3 10 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
1255 BRD-K32821942 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
1361 BRD-K32821942 U2OS 10 uM 48 h 0.0 0.0 0.0 -0.26 -0.89 0.27
13793 BRD-K32821942 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14445 BRD-K32821942 HA1E 10 uM 24 h 0.32 1.32 0.79 0.0 0.0 0.0
14802 BRD-K32821942 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
15038 BRD-K32821942 HT29 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
51142 BRD-K32821942 VCAP 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
120619 BRD-K32821942 HELA 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
120708 BRD-K32821942 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120752 BRD-K32821942 MCF??7.00 10 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
120815 BRD-K32821942 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).