CMap Candidate Details

Structure:
CMap ID: C12873
Pert ID: BRD-K32906660
Compound Name: bis-tyrphostin
Targets: EGFR
MoA: EGFR inhibitor
SMILES: Oc1ccc(/C=C(C#N)/C(=O)NCCCNC(=O)C(=Cc2ccc(O)c(O)c2)C#N)cc1O
InchiKey: ZHOKHSGWBNPFQU-GONBZBRSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1581 BRD-K32906660 HA1E 10 uM 24 h -0.23 -0.95 0.09 -0.23 -0.79 0.1
2103 BRD-K32906660 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2393 BRD-K32906660 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2662 BRD-K32906660 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41764 BRD-K32906660 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42090 BRD-K32906660 A549 10 uM 6 h -0.29 -1.2 0.55 -0.41 -1.38 2.02
42352 BRD-K32906660 ASC 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
42678 BRD-K32906660 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42982 BRD-K32906660 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.87
43315 BRD-K32906660 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.58
43543 BRD-K32906660 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43841 BRD-K32906660 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).