CMap Candidate Details

Structure:
CMap ID: C12932
Pert ID: BRD-K33106058
Compound Name: cytarabine
Targets: POLA1; POLB
MoA: Ribonucleotide reductase inhibitor
SMILES: Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1
InchiKey: UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24571 BRD-K33106058 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24765 BRD-K33106058 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25356 BRD-K33106058 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51818 BRD-K33106058 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91207 BRD-K33106058 HUH7 12.5 uM 72 h -0.24 -0.99 0.13 0.24 0.84 0.12
116274 BRD-K33106058 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116405 BRD-K33106058 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116454 BRD-K33106058 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116507 BRD-K33106058 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116555 BRD-K33106058 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121990 BRD-K33106058 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122071 BRD-K33106058 HUVEC 0.04 uM 24 h 0.24 1.02 0.12 0.0 0.0 0.0
130267 BRD-K33106058 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130372 BRD-K33106058 JURKAT 0.25 uM 24 h -0.17 -0.72 0.0 0.0 0.0 0.0
130415 BRD-K33106058 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130462 BRD-K33106058 MDAMB231 0.03 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
130504 BRD-K33106058 THP1 0.25 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
130538 BRD-K33106058 YAPC 0.08 uM 24 h 0.23 0.95 0.07 0.29 1.02 0.48
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).