CMap Candidate Details

Structure:
CMap ID: C12955
Pert ID: BRD-K33204703
Compound Name: AG-370
Targets: PDGFRB
MoA: PDGFR inhibitor
SMILES: NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N
InchiKey: CMMDWEJTQUTCKG-WUXMJOGZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2865 BRD-K33204703 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3354 BRD-K33204703 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3613 BRD-K33204703 PC3 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
3769 BRD-K33204703 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44369 BRD-K33204703 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44565 BRD-K33204703 A549 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
44928 BRD-K33204703 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45228 BRD-K33204703 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45498 BRD-K33204703 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45685 BRD-K33204703 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
46046 BRD-K33204703 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46363 BRD-K33204703 PHH 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
46682 BRD-K33204703 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99851 BRD-K33204703 U2OS 20 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).