CMap Candidate Details

Structure:
CMap ID: C01297
Pert ID: BRD-A54487287
Compound Name: cortisone-acetate
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3C(=O)C[C@]12C
InchiKey: ITRJWOMZKQRYTA-XLSOAHDVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5159 BRD-A54487287 A375 10 uM 6 h -0.23 -0.96 0.09 0.22 0.79 0.08
5267 BRD-A54487287 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5527 BRD-A54487287 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6071 BRD-A54487287 MCF??7.00 10 uM 6 h 0.3 1.27 0.58 0.0 0.0 0.0
6137 BRD-A54487287 PC3 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
6470 BRD-A54487287 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.18
41886 BRD-A54487287 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.93 0.34
42218 BRD-A54487287 ASC 10 uM 24 h 0.26 1.08 0.2 0.0 0.0 0.0
42560 BRD-A54487287 HEPG2 10 uM 6 h -0.24 -1.0 0.15 0.0 0.0 0.0
42868 BRD-A54487287 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43419 BRD-A54487287 NPC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
44016 BRD-A54487287 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).