CMap Candidate Details

Structure:
CMap ID: C12973
Pert ID: BRD-K33251802
Compound Name: miglustat
Targets: UGCG
MoA: Glycosyl transferase inhibitor
SMILES: CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InchiKey: UQRORFVVSGFNRO-UTINFBMNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91458 BRD-K33251802 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
121734 BRD-K33251802 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121840 BRD-K33251802 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
129754 BRD-K33251802 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129823 BRD-K33251802 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
129871 BRD-K33251802 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129891 BRD-K33251802 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
129914 BRD-K33251802 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129950 BRD-K33251802 MCF10A 0.08 uM 24 h 0.31 1.27 0.59 0.17 0.61 0.0
129997 BRD-K33251802 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130034 BRD-K33251802 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130106 BRD-K33251802 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130154 BRD-K33251802 YAPC 0.01 uM 24 h -0.29 -1.19 0.53 0.39 1.37 2.1
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).