CMap Candidate Details

Structure:
CMap ID: C12981
Pert ID: BRD-K33272502
Compound Name: DG-041
Targets: PTGER3
MoA: Prostanoid receptor antagonist
SMILES: Cc1cn(Cc2ccc(Cl)cc2Cl)c2c(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12
InchiKey: BFBTVZNKWXWKNZ-HWKANZROSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8935 BRD-K33272502 A375 40 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.52
9097 BRD-K33272502 A549 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9410 BRD-K33272502 AGS 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9973 BRD-K33272502 HA1E 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10341 BRD-K33272502 HCC515 40 uM 6 h 0.0 0.0 0.0 -0.37 -1.26 1.36
10505 BRD-K33272502 HCT116 40 uM 6 h 0.21 0.89 0.02 -0.35 -1.18 1.14
10776 BRD-K33272502 HEPG2 40 uM 6 h 0.0 0.0 0.0 -0.57 -1.93 15.65
10969 BRD-K33272502 HT29 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11223 BRD-K33272502 MCF??7.00 40 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
11472 BRD-K33272502 NCIH2073 40 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
11752 BRD-K33272502 NCIH508 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12036 BRD-K33272502 NCIH596 40 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
12548 BRD-K33272502 PC3 40 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
12779 BRD-K33272502 SW480 40 uM 6 h 0.0 0.0 0.0 -0.51 -1.7 15.65
13260 BRD-K33272502 U937 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13468 BRD-K33272502 VCAP 40 uM 24 h -0.27 -1.14 0.42 -0.29 -0.99 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).