CMap Candidate Details
Structure:
| CMap ID: | C12993 |
| Pert ID: | BRD-K33312228 |
| Compound Name: | halometasone |
| Targets: | NR3C1 |
| MoA: | Glucocorticoid receptor agonist |
| SMILES: | C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C(=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO)Cl |
| InchiKey: | GGXMRPUKBWXVHE-MIHLVHIWSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24429 | BRD-K33312228 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24572 | BRD-K33312228 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.45 |
| 24766 | BRD-K33312228 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24896 | BRD-K33312228 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.02 | 0.6 |
| 25094 | BRD-K33312228 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.21 | 0.75 | 0.04 |
| 25154 | BRD-K33312228 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25503 | BRD-K33312228 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |