CMap Candidate Details

Structure:
CMap ID: C13029
Pert ID: BRD-K33453211
Compound Name: levocabastine
Targets: NTSR2; HRH1
MoA: Histamine receptor antagonist
SMILES: C[C@@H]1CN(CC[C@]1(C(O)=O)c1ccccc1)[C@H]1CC[C@](CC1)(C#N)c1ccc(F)cc1
InchiKey: ZCGOMHNNNFPNMX-KYTRFIICSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4417 BRD-K33453211 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4923 BRD-K33453211 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
40793 BRD-K33453211 NEU 10 uM 24 h 0.3 1.24 0.53 0.3 1.07 0.64
41095 BRD-K33453211 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41428 BRD-K33453211 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99856 BRD-K33453211 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120559 BRD-K33453211 A549 0.04 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.73
120598 BRD-K33453211 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120622 BRD-K33453211 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.77
120661 BRD-K33453211 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120713 BRD-K33453211 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120780 BRD-K33453211 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120822 BRD-K33453211 YAPC 0.04 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
128987 BRD-K33453211 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129055 BRD-K33453211 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).