CMap Candidate Details

Structure:
CMap ID: C01303
Pert ID: BRD-A54596827
Compound Name: solifenacin
Targets: CHRM1; CHRM2; CHRM3
MoA: Acetylcholine receptor antagonist
SMILES: O=C(O[C@H]1CN2CCC1CC2)C1NCc2ccccc2[C@@H]1c1ccccc1
InchiKey: IGCKSKSSHBPKHO-LGTSYYJHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6659 BRD-A54596827 A375 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
7088 BRD-A54596827 A549 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.69 0.02
7242 BRD-A54596827 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7780 BRD-A54596827 HT29 10 uM 24 h 0.26 1.07 0.19 0.0 0.0 0.0
8163 BRD-A54596827 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8310 BRD-A54596827 PC3 10 uM 24 h -0.22 -0.92 0.06 0.4 1.4 2.18
8765 BRD-A54596827 VCAP 10 uM 6 h 0.34 1.42 1.09 0.26 0.93 0.26
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).