CMap Candidate Details

Structure:
CMap ID: C01304
Pert ID: BRD-A54632525
Compound Name: BRD-A54632525
Targets: ALOX12
MoA: Lipoxygenase inhibitor
SMILES: CC(=O)NC(c1cccs1)c1cc(Br)c2cccnc2c1O
InchiKey: FREDZQWTOHKXRX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21911 BRD-A54632525 A375 10 uM 6 h -0.24 -1.02 0.18 0.0 0.0 0.0
22099 BRD-A54632525 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
22386 BRD-A54632525 HA1E 10 uM 6 h -0.25 -1.05 0.23 0.0 0.0 0.0
22647 BRD-A54632525 HCC515 10 uM 6 h -0.27 -1.13 0.41 0.0 0.0 0.0
22928 BRD-A54632525 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.32
23234 BRD-A54632525 HT29 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.43
23513 BRD-A54632525 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.45 15.35
23788 BRD-A54632525 PC3 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
24081 BRD-A54632525 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
114961 BRD-A54632525 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).