CMap Candidate Details

Structure:
CMap ID: C13140
Pert ID: BRD-K33860217
Compound Name: CP-94253
Targets: HTR1B
MoA: Serotonin receptor agonist
SMILES: CCCOc1ccc2[nH]cc(C3=CCNCC3)c2n1
InchiKey: KWQWBZIGHIOKIO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2867 BRD-K33860217 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3178 BRD-K33860217 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3487 BRD-K33860217 PC3 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.21
3771 BRD-K33860217 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39122 BRD-K33860217 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39317 BRD-K33860217 A549 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
39674 BRD-K33860217 ASC 10 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
39987 BRD-K33860217 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40262 BRD-K33860217 HT29 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.5
40613 BRD-K33860217 MCF??7.00 10 uM 6 h -0.3 -1.24 0.65 0.0 0.0 0.0
40794 BRD-K33860217 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41096 BRD-K33860217 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41429 BRD-K33860217 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).