CMap Candidate Details

Structure:
CMap ID: C13150
Pert ID: BRD-K33882852
Compound Name: ZK-93423
Targets: GABRA1; GABRA2; GABRA3; GABRA5
MoA: Benzodiazepine receptor agonist
SMILES: CCOC(=O)c1ncc2[nH]c3ccc(OCc4ccccc4)cc3c2c1COC
InchiKey: ALBKMJDFBZVHAK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3355 BRD-K33882852 HCC515 10 uM 6 h -0.19 -0.79 0.0 0.35 1.23 1.23
3772 BRD-K33882852 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46050 BRD-K33882852 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46685 BRD-K33882852 SKB 10 uM 24 h -0.25 -1.03 0.19 0.0 0.0 0.0
53393 BRD-K33882852 HEPG2 2.5 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
53507 BRD-K33882852 HUH7 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.35
53655 BRD-K33882852 PHH 2.5 uM 24 h -0.22 -0.92 0.06 0.27 0.94 0.29
99861 BRD-K33882852 U2OS 10 uM 6 h 0.2 0.85 0.01 -0.3 -1.01 0.58
120564 BRD-K33882852 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120601 BRD-K33882852 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
120625 BRD-K33882852 HELA 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
120667 BRD-K33882852 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.26
120719 BRD-K33882852 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120758 BRD-K33882852 MCF??7.00 1.11 uM 24 h 0.26 1.09 0.24 0.0 0.0 0.0
120828 BRD-K33882852 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.25
128988 BRD-K33882852 A375 2.22 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
129081 BRD-K33882852 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).