CMap Candidate Details

Structure:
CMap ID: C13195
Pert ID: BRD-K34014345
Compound Name: naproxol
Targets: PTGS1; PTGS2
MoA: Anti-inflammatory agent
SMILES: COc1ccc2cc(ccc2c1)[C@H](C)CO
InchiKey: LTRANDSQVZFZDG-SNVBAGLBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5318 BRD-K34014345 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
5768 BRD-K34014345 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.12 0.94
5903 BRD-K34014345 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.16 -0.53 0.0
6018 BRD-K34014345 HT29 10 uM 6 h 0.23 0.95 0.06 0.0 0.0 0.0
6271 BRD-K34014345 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6355 BRD-K34014345 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37144 BRD-K34014345 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37281 BRD-K34014345 A549 10 uM 24 h -0.27 -1.12 0.38 -0.28 -0.94 0.39
37637 BRD-K34014345 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
38198 BRD-K34014345 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
38463 BRD-K34014345 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38709 BRD-K34014345 PHH 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).