CMap Candidate Details

Structure:
CMap ID: C01322
Pert ID: BRD-A55416093
Compound Name: colforsin
Targets: ADCY2; ADCY5
MoA: Adenylyl cyclase activator
SMILES: CC(=O)O[C@H]1[C@@H](O)C2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
InchiKey: OHCQJHSOBUTRHG-VDCUXWMXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5405 BRD-A55416093 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.8
5730 BRD-A55416093 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5846 BRD-A55416093 HEPG2 10 uM 6 h 0.24 0.98 0.09 -0.3 -1.01 0.57
6072 BRD-A55416093 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.34
6138 BRD-A55416093 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6472 BRD-A55416093 VCAP 10 uM 6 h 0.19 0.78 0.0 -0.35 -1.18 1.14
37086 BRD-A55416093 A375 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.16 1.1
37347 BRD-A55416093 A549 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.24 1.35
37519 BRD-A55416093 ASC 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.7
38024 BRD-A55416093 HT29 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.16 1.11
38368 BRD-A55416093 NPC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
38872 BRD-A55416093 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96029 BRD-A55416093 PHH 3.33 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).