CMap Candidate Details

Structure:
CMap ID: C13238
Pert ID: BRD-K34170797
Compound Name: fexaramine
Targets: NR1H4
MoA: FXR agonist
SMILES: COC(=O)C=Cc1cccc(c1)N(Cc2ccc(cc2)c3ccc(cc3)N(C)C)C(=O)C4CCCCC4
InchiKey: VLQTUNDJHLEFEQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3009 BRD-K34170797 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3181 BRD-K34170797 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3490 BRD-K34170797 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3955 BRD-K34170797 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44373 BRD-K34170797 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44572 BRD-K34170797 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
44935 BRD-K34170797 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45234 BRD-K34170797 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45503 BRD-K34170797 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45688 BRD-K34170797 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46054 BRD-K34170797 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
46370 BRD-K34170797 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46689 BRD-K34170797 SKB 10 uM 24 h -0.26 -1.08 0.29 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).