CMap Candidate Details

Structure:
CMap ID: C13282
Pert ID: BRD-K34328244
Compound Name: MF-101
Targets: ESR2; XDH
MoA: Estrogen receptor agonist
SMILES: Oc1ccc(cc1)[C@@H]1CC(=O)c2ccc(O)cc2O1
InchiKey: FURUXTVZLHCCNA-AWEZNQCLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124939 BRD-K34328244 A375 0.125 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
124967 BRD-K34328244 A549 0.125 uM 24 h -0.34 -1.42 1.43 0.0 0.0 0.0
124999 BRD-K34328244 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125028 BRD-K34328244 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125055 BRD-K34328244 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125111 BRD-K34328244 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
125132 BRD-K34328244 PC3 0.04 uM 24 h 0.18 0.76 0.0 -0.28 -0.94 0.37
125165 BRD-K34328244 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133051 BRD-K34328244 HEK293 2.22 uM 24 h 0.0 0.0 0.0 -0.47 -1.57 15.65
133158 BRD-K34328244 JURKAT 0.08 uM 24 h 0.28 1.17 0.37 0.0 0.0 0.0
133198 BRD-K34328244 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133227 BRD-K34328244 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133317 BRD-K34328244 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).