CMap Candidate Details
Structure:
CMap ID: | C13290 |
Pert ID: | BRD-K34341643 |
Compound Name: | glasdegib |
Targets: | -- |
MoA: | -- |
SMILES: | CN1CC[C@H](C[C@@H]1c1nc2ccccc2[nH]1)NC(=O)Nc1ccc(cc1)C#N |
InchiKey: | SFNSLLSYNZWZQG-VQIMIIECSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
120567 | BRD-K34341643 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
120606 | BRD-K34341643 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.12 | 0.76 |
120672 | BRD-K34341643 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
120725 | BRD-K34341643 | JURKAT | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
120833 | BRD-K34341643 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.66 | 0.01 |
128990 | BRD-K34341643 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
129039 | BRD-K34341643 | HELA | 0.08 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.63 |
129060 | BRD-K34341643 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.86 | 0.16 |
129083 | BRD-K34341643 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |