CMap Candidate Details

Structure:
CMap ID: C13320
Pert ID: BRD-K34415467
Compound Name: trimethobenzamide
Targets: DRD2
MoA: Histamine receptor antagonist
SMILES: COc1cc(cc(OC)c1OC)C(=O)NCc1ccc(OCCN(C)C)cc1
InchiKey: FEZBIKUBAYAZIU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4418 BRD-K34415467 HCC515 10 uM 24 h 0.18 0.74 0.0 0.0 0.0 0.0
5076 BRD-K34415467 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
37145 BRD-K34415467 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37282 BRD-K34415467 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37639 BRD-K34415467 ASC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.98
38465 BRD-K34415467 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38711 BRD-K34415467 PHH 10 uM 24 h 0.23 0.96 0.08 0.0 0.0 0.0
121789 BRD-K34415467 HT29 1.11 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
129784 BRD-K34415467 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129818 BRD-K34415467 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
129868 BRD-K34415467 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129945 BRD-K34415467 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129993 BRD-K34415467 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
130029 BRD-K34415467 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130077 BRD-K34415467 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130101 BRD-K34415467 THP1 0.08 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
130150 BRD-K34415467 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).