CMap Candidate Details

Structure:
CMap ID: C13328
Pert ID: BRD-K34441861
Compound Name: moexipril
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(O)=O
InchiKey: UWWDHYUMIORJTA-HSQYWUDLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1582 BRD-K34441861 HA1E 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
1915 BRD-K34441861 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2187 BRD-K34441861 PC3 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
2676 BRD-K34441861 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
41765 BRD-K34441861 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41930 BRD-K34441861 A549 10 uM 24 h -0.25 -1.04 0.21 -0.41 -1.38 2.02
42353 BRD-K34441861 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42679 BRD-K34441861 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42983 BRD-K34441861 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43185 BRD-K34441861 MCF??7.00 10 uM 24 h -0.24 -1.0 0.14 -0.4 -1.33 1.85
43544 BRD-K34441861 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43842 BRD-K34441861 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44109 BRD-K34441861 SKB 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).