CMap Candidate Details

Structure:
CMap ID: C13391
Pert ID: BRD-K34608650
Compound Name: GP-2a
Targets: CNR2
MoA: Cannabinoid receptor agonist
SMILES: Cc1ccc-2c(Cc3c(nn(c-23)-c2ccc(Cl)cc2Cl)C(=O)NC2CCCCC2)c1
InchiKey: SPEFJYZGXZENAF-UHFFFAOYSA-N
Compound Aliases: GP-2A

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2871 BRD-K34608650 HA1E 10 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
3183 BRD-K34608650 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3491 BRD-K34608650 PC3 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
3956 BRD-K34608650 VCAP 10 uM 6 h -0.23 -0.94 0.08 0.26 0.93 0.26
44374 BRD-K34608650 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44573 BRD-K34608650 A549 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
44936 BRD-K34608650 ASC 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
45235 BRD-K34608650 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.23
45504 BRD-K34608650 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45810 BRD-K34608650 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46055 BRD-K34608650 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46371 BRD-K34608650 PHH 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
46690 BRD-K34608650 SKB 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
99867 BRD-K34608650 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).