CMap Candidate Details

Structure:
CMap ID: C01340
Pert ID: BRD-A55946879
Compound Name: BW-B70C
Targets: ALOX5
MoA: Lipoxygenase inhibitor
SMILES: CC(C=Cc1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O
InchiKey: UAIYNMRLUHHRMF-AATRIKPKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6661 BRD-A55946879 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6942 BRD-A55946879 A549 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
7245 BRD-A55946879 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7562 BRD-A55946879 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7783 BRD-A55946879 HT29 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
8050 BRD-A55946879 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8312 BRD-A55946879 PC3 10 uM 24 h 0.18 0.75 0.0 -0.32 -1.06 0.73
8767 BRD-A55946879 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).