CMap Candidate Details

Structure:
CMap ID: C13417
Pert ID: BRD-K34713073
Compound Name: PD-123319
Targets: AGTR2
MoA: Angiotensin antagonist
SMILES: CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C
InchiKey: YSTVFDAKLDMYCR-NDEPHWFRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120569 BRD-K34713073 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120607 BRD-K34713073 HA1E 1.11 uM 24 h -0.25 -1.05 0.24 -0.2 -0.67 0.02
120674 BRD-K34713073 HT29 0.37 uM 24 h 0.31 1.28 0.64 0.0 0.0 0.0
120727 BRD-K34713073 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120786 BRD-K34713073 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120835 BRD-K34713073 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128991 BRD-K34713073 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129023 BRD-K34713073 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129062 BRD-K34713073 MCF??7.00 0.03 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).