CMap Candidate Details

Structure:
CMap ID: C01343
Pert ID: BRD-A56012032
Compound Name: thiorphan
Targets: MME
MoA: Membrane metalloendopeptidase inhibitor
SMILES: OC(=O)CNC(=O)C(CS)Cc1ccccc1
InchiKey: LJJKNPQAGWVLDQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5406 BRD-A56012032 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5530 BRD-A56012032 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5848 BRD-A56012032 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5984 BRD-A56012032 HT29 10 uM 6 h 0.25 1.03 0.13 -0.26 -0.86 0.22
6473 BRD-A56012032 VCAP 10 uM 6 h 0.0 0.0 0.0 0.23 0.82 0.1
44251 BRD-A56012032 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44485 BRD-A56012032 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44776 BRD-A56012032 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45746 BRD-A56012032 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45895 BRD-A56012032 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46212 BRD-A56012032 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46527 BRD-A56012032 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96520 BRD-A56012032 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).