CMap Candidate Details

Structure:
CMap ID: C13464
Pert ID: BRD-K34870043
Compound Name: adoprazine
Targets: DRD2; HTR1A
MoA: Serotonin receptor agonist; Dopamine receptor antagonist
SMILES: Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2cccc3OCCOc23)c1
InchiKey: IUVSEUFHPNITEQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120531 BRD-K34870043 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120570 BRD-K34870043 A549 0.04 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.55
120637 BRD-K34870043 HELA 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120675 BRD-K34870043 HT29 0.04 uM 24 h 0.2 0.82 0.0 0.23 0.8 0.08
120728 BRD-K34870043 JURKAT 10 uM 24 h -0.26 -1.07 0.28 -0.34 -1.13 0.98
120836 BRD-K34870043 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129009 BRD-K34870043 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129063 BRD-K34870043 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
129084 BRD-K34870043 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).