CMap Candidate Details

Structure:
CMap ID: C13499
Pert ID: BRD-K34995470
Compound Name: SU-1498
Targets: ERBB2
MoA: VEGFR inhibitor
SMILES: CC(C)c1cc(/C=C(C#N)/C(=O)NCCCc2ccccc2)cc(C(C)C)c1O
InchiKey: JANPYFTYAGTSIN-FYJGNVAPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4101 BRD-K34995470 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4420 BRD-K34995470 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4680 BRD-K34995470 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5078 BRD-K34995470 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39123 BRD-K34995470 A375 10 uM 6 h -0.22 -0.92 0.06 -0.31 -1.05 0.71
39676 BRD-K34995470 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39989 BRD-K34995470 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40264 BRD-K34995470 HT29 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
40464 BRD-K34995470 MCF??7.00 10 uM 24 h -0.19 -0.8 0.0 -0.25 -0.85 0.19
40796 BRD-K34995470 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41098 BRD-K34995470 NPC 10 uM 24 h -0.26 -1.06 0.26 -0.28 -0.95 0.39
41431 BRD-K34995470 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99870 BRD-K34995470 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).