CMap Candidate Details

Structure:
CMap ID: C00135
Pert ID: BRD-A05352148
Compound Name: ipratropium
Targets: CHRM1; CHRM2; CHRM3; CHRM4
MoA: Acetylcholine receptor antagonist
SMILES: CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)c1ccccc1
InchiKey: OEXHQOGQTVQTAT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5817 BRD-A05352148 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6433 BRD-A05352148 VCAP 10 uM 24 h 0.31 1.29 0.65 -0.48 -1.61 15.65
44471 BRD-A05352148 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44742 BRD-A05352148 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45346 BRD-A05352148 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45606 BRD-A05352148 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45863 BRD-A05352148 NPC 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
46175 BRD-A05352148 PHH 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
46490 BRD-A05352148 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
49751 BRD-A05352148 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50091 BRD-A05352148 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50278 BRD-A05352148 HCC515 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
50798 BRD-A05352148 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).