CMap Candidate Details

Structure:
CMap ID: C13581
Pert ID: BRD-K35245662
Compound Name: ciclesonide
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC(C)C(=O)OCC(=O)[C@@]12O[C@@H](O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
InchiKey: LUKZNWIVRBCLON-GXOBDPJESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120532 BRD-K35245662 A375 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
120571 BRD-K35245662 A549 10 uM 24 h -0.26 -1.08 0.29 -0.25 -0.83 0.16
120628 BRD-K35245662 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120676 BRD-K35245662 HT29 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
120729 BRD-K35245662 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
120787 BRD-K35245662 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120837 BRD-K35245662 YAPC 10 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
129010 BRD-K35245662 HA1E 2.22 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
129064 BRD-K35245662 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).