CMap Candidate Details

Structure:
CMap ID: C13628
Pert ID: BRD-K35430135
Compound Name: SR-59230A
Targets: ADRB3
MoA: Adrenergic receptor antagonist
SMILES: CCc1ccccc1OC[C@@H](O)CN[C@H]1CCCc2ccccc12
InchiKey: VFDHMSXXELYMRW-ICSRJNTNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4217 BRD-K35430135 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.12
4422 BRD-K35430135 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4681 BRD-K35430135 PC3 10 uM 24 h -0.18 -0.76 0.0 -0.24 -0.82 0.15
4924 BRD-K35430135 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39124 BRD-K35430135 A375 10 uM 6 h -0.19 -0.81 0.0 0.3 1.04 0.56
39445 BRD-K35430135 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39678 BRD-K35430135 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39991 BRD-K35430135 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.33
40265 BRD-K35430135 HT29 10 uM 6 h 0.0 0.0 0.0 0.21 0.75 0.04
40614 BRD-K35430135 MCF??7.00 10 uM 6 h -0.19 -0.77 0.0 0.22 0.79 0.07
40798 BRD-K35430135 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41100 BRD-K35430135 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41433 BRD-K35430135 SKB 10 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
99873 BRD-K35430135 U2OS 10 uM 6 h 0.25 1.06 0.18 -0.22 -0.73 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).