CMap Candidate Details

Structure:
CMap ID: C01364
Pert ID: BRD-A56892734
Compound Name: esomeprazole
Targets: ATP4A
MoA: ATPase inhibitor
SMILES: COc1ccc2n([Mg]n3c(nc4cc(OC)ccc34)S(=O)Cc5ncc(C)c(OC)c5C)c(nc2c1)S(=O)Cc6ncc(C)c(OC)c6C
InchiKey: KWORUUGOSLYAGD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24390 BRD-A56892734 A375 10 uM 6 h -0.19 -0.78 0.0 0.0 0.0 0.0
24537 BRD-A56892734 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24729 BRD-A56892734 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24850 BRD-A56892734 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25072 BRD-A56892734 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25220 BRD-A56892734 PC3 10 uM 6 h 0.27 1.15 0.32 0.0 0.0 0.0
25478 BRD-A56892734 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).