CMap Candidate Details

Structure:
CMap ID: C13649
Pert ID: BRD-K35483542
Compound Name: alitretinoin
Targets: RARA; RARB; RARG; RXRA; RXRB; RXRG
MoA: Retinoid receptor agonist
SMILES: C/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C
InchiKey: SHGAZHPCJJPHSC-ZVCIMWCZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
26672 BRD-K35483542 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27541 BRD-K35483542 MCF??7.00 10 uM 24 h -0.26 -1.09 0.32 0.0 0.0 0.0
28861 BRD-K35483542 PHH 10 uM 24 h 0.24 1.01 0.12 -0.29 -0.98 0.47
34090 BRD-K35483542 ASC 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
34607 BRD-K35483542 HCC515 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
34874 BRD-K35483542 HEPG2 10 uM 6 h -0.32 -1.34 0.98 0.0 0.0 0.0
35137 BRD-K35483542 HT29 10 uM 6 h 0.23 0.95 0.06 0.23 0.82 0.1
35560 BRD-K35483542 NEU 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
36547 BRD-K35483542 SKB 10 uM 24 h -0.3 -1.25 0.68 0.0 0.0 0.0
36813 BRD-K35483542 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95500 BRD-K35483542 A549 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95658 BRD-K35483542 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
96446 BRD-K35483542 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96515 BRD-K35483542 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98753 BRD-K35483542 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).