CMap Candidate Details

Structure:
CMap ID: C01366
Pert ID: BRD-A56987319
Compound Name: SQ-22536
Targets: ADCY1
MoA: Adenylyl cyclase inhibitor
SMILES: Nc1ncnc2n(cnc12)C1CCCO1
InchiKey: UKHMZCMKHPHFOT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2969 BRD-A56987319 HA1E 10 uM 6 h -0.16 -0.66 0.0 -0.32 -1.07 0.75
3110 BRD-A56987319 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3445 BRD-A56987319 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3693 BRD-A56987319 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44252 BRD-A56987319 A375 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.7
44777 BRD-A56987319 ASC 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.38
45096 BRD-A56987319 HEPG2 10 uM 6 h -0.25 -1.06 0.25 0.3 1.08 0.64
45369 BRD-A56987319 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45616 BRD-A56987319 MCF??7.00 10 uM 24 h 0.18 0.74 0.0 0.0 0.0 0.0
45896 BRD-A56987319 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46213 BRD-A56987319 PHH 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
46528 BRD-A56987319 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96086 BRD-A56987319 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100235 BRD-A56987319 U2OS 25 uM 6 h 0.28 1.17 0.37 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).