CMap Candidate Details

Structure:
CMap ID: C13662
Pert ID: BRD-K35531059
Compound Name: molsidomine
Targets: GUCY1A1
MoA: Guanylyl cyclase activator
SMILES: CCOC(=O)/N=c1/c[n+]([n-]o1)N2CCOCC2
InchiKey: XLFWDASMENKTKL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2872 BRD-K35531059 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3358 BRD-K35531059 HCC515 10 uM 6 h -0.19 -0.79 0.0 -0.3 -1.0 0.54
3776 BRD-K35531059 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44375 BRD-K35531059 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44696 BRD-K35531059 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45236 BRD-K35531059 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
45505 BRD-K35531059 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45811 BRD-K35531059 MCF??7.00 10 uM 6 h -0.23 -0.96 0.09 0.0 0.0 0.0
46056 BRD-K35531059 NPC 10 uM 24 h 0.0 0.0 0.0 0.26 0.94 0.28
46372 BRD-K35531059 PHH 10 uM 24 h 0.22 0.91 0.03 0.39 1.38 2.16
46691 BRD-K35531059 SKB 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.04
51820 BRD-K35531059 PC3 10 uM 24 h -0.25 -1.06 0.26 -0.32 -1.07 0.76
91103 BRD-K35531059 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).