CMap Candidate Details

Structure:
CMap ID: C13669
Pert ID: BRD-K35559145
Compound Name: levomepromazine
Targets: DRD2; DRD3; DRD4
MoA: Dopamine receptor antagonist
SMILES: COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1
InchiKey: VRQVVMDWGGWHTJ-CQSZACIVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3010 BRD-K35559145 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3184 BRD-K35559145 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3614 BRD-K35559145 PC3 10 uM 6 h -0.3 -1.25 0.68 0.0 0.0 0.0
3777 BRD-K35559145 VCAP 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
42092 BRD-K35559145 A549 10 uM 6 h 0.0 0.0 0.0 0.26 0.94 0.28
42355 BRD-K35559145 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42681 BRD-K35559145 HEPG2 10 uM 6 h -0.26 -1.07 0.27 0.0 0.0 0.0
42985 BRD-K35559145 HT29 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.69 0.02
43187 BRD-K35559145 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43546 BRD-K35559145 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.71
43844 BRD-K35559145 PHH 10 uM 24 h -0.21 -0.88 0.03 0.31 1.11 0.74
44111 BRD-K35559145 SKB 10 uM 24 h -0.18 -0.77 0.0 -0.21 -0.72 0.04
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).